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活動報告

2021

 2021

Original Articles

  1. H. Nagano, S. Ito, T. Masuda, S. Ohtsuki: Effect of Insulin Receptor-Knockdown on the Expression Levels of Blood-Brain Barrier Functional Proteins in Human Brain Microvascular Endothelial Cells. Pharm Res. (2021)
  2. K. Chida, Y. Sakurai, A. Ohtani, T. Masuda, S. Ohtsuki, H. Tanaka, H. Akita: Proteomics Analysis of Lymphatic Metastasis-Related Proteins Using Highly Metastatic Human Melanoma Cells Originated by Sequential in Vivo Implantation. Biol Pharm Bull. 44:1551-1556 (2021)
  3. D. Hatakeyama, T. Masuda, R. Miki, S. Ohtsuki, T. Kuzuhara: In-vitro acetylation of SARS-CoV and SARS-CoV-2 nucleocapsid proteins by human PCAF and GCN5. Biochem Biophys Res Commun. 557:273-279 (2021)
  4. H. Ohguchi, P.M.C. Park, T. Wang, B.E. Gryder, D. Ogiya, K. Kurata, X. Zhang, D. Li, C. Pei, T. Masuda, C. Johansson, V.K. Wimalasena, Y. Kim, S. Hino, S. Usuki, Y. Kawano, M.K. Samur, Y.-T. Tai, N.C. Munshi, M. Matsuoka, S. Ohtsuki, M. Nakao, T. Minami, S. Lauberth, J. Khan, U. Oppermann, A.D. Durbin, K.C. Anderson, T. Hideshima, J. Qi: Lysine Demethylase 5A Is Required for MYC-Driven Transcription in Multiple Myeloma. Blood Cancer Discovery. 2: 370 (2021)
  5. S. Ito, Y. Torii, S. Chikamatsu, T. Harada, S. Yamaguchi, S. Ogata, K. Sonoda, T. Wakayama, T. Masuda, S. Ohtsuki: Oral Coadministration of Zn-Insulin with d-Form Small Intestine-Permeable Cyclic Peptide Enhances Its Blood Glucose-Lowering Effect in Mice. Mol Pharm. 18:1593-1603 (2021)
  6. K. Omachi, S. Kaseda, T. Yokota, M. Kamura, K. Teramoto, J. Kuwazuru, H. Kojima, H. Nohara, K. Koyama, S. Ohtsuki, S. Misumi, T. Takeo, N. Nakagata, J.D. Li, T. Shuto, M.A. Suico, J.H. Miner, H. Kai: Metformin ameliorates the severity of experimental Alport syndrome. Sci Rep. 11:7053 (2021)
  7. S. Ito, W. Lee, J.E. Park, M. Yasunaga, A. Mori, S. Ohtsuki, Y. Sugiyama: Transient, Tunable Expression of NTCP and BSEP in MDCKII Cells for Kinetic Delineation of the Rate-Determining Process and Inhibitory Effects of Rifampicin in Hepatobiliary Transport of Taurocholate. J Pharm Sci. 110:365-375 (2021)
  8. H. Terai, J. Hamamoto, T. Manabe, K. Emoto, T. Masuda, S. Kuronuma, K. Kobayashi, K. Masuzawa, S. Ikemura, S. Nakayama, I. Kawada, Y. Suzuki, O. Takeuchi, Y. Suzuki, S. Ohtsuki, H. Yasuda, K. Soejima, K. Fukunaga: SHOC2 is a critical modulator of the sensitivity to EGFR-TKI in non-small cell lung cancer cells. Cancer Research 19:317–28 (2021)

Review Articles

  1. T. Masuda, S. Ito, S. Ohtsuki: Advances in sample preparation for membrane proteome quantification. Drug Discovery Today: Technologies. (2021)
  2. T. Masuda, A. Mori, S. Ito, S. Ohtsuki: Quantitative and targeted proteomics-based identification and validation of drug efficacy biomarkers. Drug Metab Pharmacokinet. 36:100361 (2021)