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活動報告

2019 Publications

2019/03/06

Original Articles

  1. N. Tateshita, N. Miura, H. Tanaka, T. Masuda, S. Ohtsuki, K. Tange, Y. Nakai, H. Yoshioka, H. Akita: Development of a lipoplex-type mRNA carrier composed of an ionizable lipid with a vitamin E scaffold and the KALA peptide for use as an ex vivo dendritic cell-based cancer vaccine. Journal of Controlled Release. 30:36-46 (2019)
  2. S. Ogata, S. Ito, T. Masuda, S. Ohtsuki: Changes of Blood-Brain Barrier and Brain Parenchymal Protein Expression Levels of Mice under Different Insulin-Resistance Conditions Induced by High-Fat Diet. Pharmaceutical research. 36:141 (2019)
  3. M. Nambu, T. Masuda, S. Ito, K. Kato, T. Kojima, H. Daiko, Y. Ito, K. Honda, S. Ohtsuki: Leucine-rich alpha-2-glycoprotein 1 in serum is a possible biomarker to predict response to preoperative chemoradiotherapy for esophageal cancer. Biol Pharm Bull. 42:1766-1771 (2019)
  4. E. Takeo, Y. Sugiura, T. Uemura, K. Nishimoto, M. Yasuda, E. Sugiyama, S. Ohtsuki, T. Higashi, T. Nishikawa, M. Suematsu, E. Fukusaki, S. Shimma: Tandem Mass Spectrometry Imaging Reveals Distinct Accumulation Patterns of Steroid Structural Isomers in Human Adrenal Glands.  Anal Chem.  91:8918-8925 (2019)
  5. T. Masuda, T. Hoshiyama, T. Uemura, M. Hirayama-Kurogi, S. Ogata, A. Furukawa, P.O. Couraud, T. Furihata, S. Ito, S. Ohtsuki: Large-Scale Quantitative Comparison of Plasma Transmembrane Proteins between Two Human Blood-Brain Barrier Model Cell Lines, hCMEC/D3 and HBMEC/cibeta.  Mol Pharm.  16:2162-2171 (2019)
  6. T. Kuno, M. Hirayama-Kurogi, S. Ito, S. Ohtsuki: Proteomic analysis of small intestinal epithelial cells in antibiotic-treated mice: Changes in drug transporters and metabolizing enzymes.  Drug Metab Pharmacokinet.  34:159-162 (2019)
  7. S. Ito, G. Honda, Y. Fujino, S. Ogata, M. Hirayama-Kurogi, S. Ohtsuki: Knockdown of Orphan Transporter SLC22A18 Impairs Lipid Metabolism and Increases Invasiveness of HepG2 Cells.  Pharm Res.  36:39 (2019)
  8. Y. Hoshi, Y. Uchida, M. Tachikawa, S. Ohtsuki, P.O. Couraud, T. Suzuki, T. Terasaki: Oxidative stress-induced activation of Abl and Src kinases rapidly induces P-glycoprotein internalization via phosphorylation of caveolin-1 on tyrosine-14, decreasing cortisol efflux at the blood-brain barrier.  J Cereb Blood Flow Metab.  271678X18822801 (2019)
  9. T. Kimura, A. Tsukada, T. Fukutomi, K. Ichida, S. Ohtsuki, H. Sakurai: Urate Transport via Paracellular Route across Epithelial Cells.  Biol Pharm Bull.  42:43-49 (2019)
  10. D. Kobayashi, T. Tokuda, K. Sato, H. Okanishi, M. Nagayama, M. Hirayama-Kurogi, S. Ohtsuki, N. Araki: Identification of a Specific Translational Machinery via TCTP-EF1A2 Interaction Regulating NF1-associated Tumor Growth by Affinity Purification and Data-independent Mass Spectrometry Acquisition (AP-DIA).  Mol Cell Proteomics.  18:245-262 (2019)
  11. S. Nishiumi, T. Kohata, T. Kobayashi, Y. Kodama, S. Ohtsuki, M. Yoshida: Comparison of venous and fingertip plasma using non-targeted proteomics and metabolomics.  Talanta.  192:182-188 (2019)

著書

    1. 米山敏広、大槻純男:第6章 早期膵がんの血中バイオマーカーへの新しいアプローチ、「早期発見・予防にむけた次世代がん検査技術の最前線」、シーエムシー出版、54-62 (2019)