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活動報告

2017 Publications

2017/04/18

Original Articles

  1. K. Shirotani, K. Matsuo, S. Ohtsuki, T. Masuda, M. Asai, Y. Kutoku, Y. Ohsawa, Y. Sunada, T. Kondo, H. Inoue, N. Iwata: A simplified and sensitive method to identify Alzheimer’s disease biomarker candidates using patient-derived induced pluripotent stem cells (iPSCs).  J Biochem. 162:391-394 (2017)
  2. H. Nagahori, K. Nakamura, K. Sumida, S. Ito, S. Ohtsuki: Combining genomics to identify the pathways of post-transcriptional non-genotoxic signaling and energy homeostasis in livers of rats treated with the PXR agonist, PCN.  J Proteome Res. 16:3634-3645 (2017)
  3. B.C. Collins, C.L. Hunter, Y. Liu, B. Schilling, G. Rosenberger, S.L. Bader, D.W. Chan, B.W. Gibson, A.C. Gingras, J.M. Held, M. Hirayama-Kurogi, G. Hou, C. Krisp, B. Larsen, L. Lin, S. Liu, M.P. Molloy, R.L. Moritz, S. Ohtsuki, R. Schlapbach, N. Selevsek, S.N. Thomas, S.C. Tzeng, H. Zhang, R. Aebersold: Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry.  Nat Commun.  8:291 (2017)
  4. S. Yamaguchi, S. Ito, M. Kurogi-Hirayama, S. Ohtsuki: Identification of cyclic peptides for facilitation of transcellular transport of phages across intestinal epithelium in vitro and in vivo.  J Control Release.  262:232-238 (2017)
  5. S. Ito, M. Yanai, S. Yamaguchi, P.O. Couraud, S. Ohtsuki: Regulation of Tight-Junction Integrity by Insulin in an In Vitro Model of Human Blood-Brain Barrier.  J Pharm Sci.  106:2599-2605 (2017)
  6. M. Hirayama-Kurogi, Y. Takizawa, Y. Kunii, J. Matsumoto, A. Wada, M. Hino, H. Akatsu, Y. Hashizume, S. Yamamoto, T. Kondo, S. Ito, M. Tachikawa, S.I. Niwa, H. Yabe, T. Terasaki, M. Setou, S. Ohtsuki: Downregulation of GNA13-ERK network in prefrontal cortex of schizophrenia brain identified by combined focused and targeted quantitative proteomics.  J Proteomics.  158:31-42 (2017)
  7. T. Yoneyama, S. Ohtsuki, M. Tachikawa, Y. Uchida, T. Terasaki: Scrambled Internal Standard (sIS) Method for High-Throughput Protein Quantification by MALDI-MS/MS.  J Proteome Res. 16:1556-1565 (2017)
  8. Y. Hoshi, Y. Uchida, M. Tachikawa, S. Ohtsuki, T. Terasaki: Actin filament-associated protein 1 (AFAP-1) is a key mediator in inflammatory signaling-induced rapid attenuation of intrinsic P-gp function in human brain capillary endothelial cells.  Journal of Neurochemistry.  141:247-262 (2017)
  9. T. Uemura, S. Ito, Y. Ohta, M. Tachikawa, T. Wada, T. Terasaki, S. Ohtsuki: Abnormal N-Glycosylation of a Novel Missense Creatine Transporter Mutant, G561R, Associated with Cerebral Creatine Deficiency Syndromes Alters Transporter Activity and Localization.  Biol Pharm Bull.  40:49-55 (2017)
  10. H. Kuroda, M. Tachikawa, Y. Uchida, K. Inoue, H. Ohtsuka, S. Ohtsuki, M. Unno, T. Terasaki: All-trans retinoic acid enhances gemcitabine cytotoxicity in human pancreatic cancer cell line AsPC-1 by up-regulating protein expression of deoxycytidine kinase.  Eur J Pharm Sci.  103:116-121 (2017)
  11. T. Miura, M. Tachikawa, H. Ohtsuka, K. Fukase, S. Nakayama, N. Sakata, F. Motoi, T. Naitoh, Y. Katayose, Y. Uchida, S. Ohtsuki, T. Terasaki, M. Unno: Application of Quantitative Targeted Absolute Proteomics to Profile Protein Expression Changes of Hepatic Transporters and Metabolizing Enzymes During Cholic Acid-Promoted Liver Regeneration.  J Pharm Sci.  106:2499-2508 (2017)
  12. S. Nakamura, H. Osaka, S.I. Muramatsu, N. Takino, M. Ito, S. Aoki, E.F. Jimbo, K. Shimazaki, T. Onaka, S. Ohtsuki, T. Terasaki, T. Yamagata: Gene therapy for a mouse model of glucose transporter-1 deficiency syndrome.  Mol Genet Metab Rep.  10:67-74 (2017)
  13. Y. Ochiai, Y. Uchida, S. Ohtsuki, M. Tachikawa, S. Aizawa, T. Terasaki: The blood-brain barrier fatty acid transport protein 1 (FATP1/SLC27A1) supplies docosahexaenoic acid to the brain, and insulin facilitates transport.  J Neurochem.  141:400-412 (2017)
総説
  1. 増田豪、緒方星陵、高畑智宏、伊藤慎悟、大槻純男:定量プロテオミクスの薬物治療、診断への展開、臨床化学、46:283-290 (2017)