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活動報告

2013 Publications

2017/03/23
Original Articles
  1. S. Ito, K. Matsumiya, S. Ohtsuki, J. Kamiie, T. Terasaki:Contributions of degradation and brain-to-blood elimination across the blood-brain barrier to cerebral clearance of human amyloid-beta peptide(1-40) in mouse brain.J Cereb Blood Flow Metab.33:1770-7 (2013)
  2. Y. Uchida, M. Tachikawa, W. Obuchi, Y. Hoshi, Y. Tomioka, S. Ohtsuki, T. Terasaki:A study protocol for quantitative targeted absolute proteomics (QTAP) by LC-MS/MS: application for inter-strain differences in protein expression levels of transporters, receptors, claudin-5, and marker proteins at the blood-brain barrier in ddY, FVB, and C57BL/6J mice.Fluids Barriers CNS.10:21 (2013)
  3. Y. Hoshi, Y. Uchida, M. Tachikawa, T. Inoue, S. Ohtsuki, T. Terasaki:Quantitative atlas of blood-brain barrier transporters, receptors, and tight junction proteins in rats and common marmoset.J Pharm Sci.(2013)
  4. A. Sakamoto, T. Matsumaru, N. Yamamura, Y. Uchida, M. Tachikawa, S. Ohtsuki, T. Terasaki:Quantitative expression of human drug transporter proteins in lung tissues: Analysis of regional, gender, and interindividual differences by liquid chromatography-tandem mass spectrometry.J Pharm Sci.(2013)
  5. T. Yoneyama, S. Ohtsuki, M. Ono, K. Ohmine, Y. Uchida, T. Yamada, M. Tachikawa, T. Terasaki:Quantitative Targeted Absolute Proteomics-Based Large-Scale Quantification of Proline-Hydroxylated alpha-Fibrinogen in Plasma for Pancreatic Cancer Diagnosis.J Proteome Res.12:753-62 (2013)
  6. W. Obuchi, S. Ohtsuki, Y. Uchida, K. Ohmine, T. Yamori, T. Terasaki:Identification of transporters associated with Etoposide sensitivity of stomach cancer cell lines and methotrexate sensitivity of breast cancer cell lines by quantitative targeted absolute proteomics.Mol Pharmacol.83:490-500 (2013)
  7. Y. Kazuki, K. Kobayashi, S. Aueviriyavit, T. Oshima, Y. Kuroiwa, Y. Tsukazaki, N. Senda, H. Kawakami, S. Ohtsuki, S. Abe, M. Takiguchi, H. Hoshiya, N. Kajitani, S. Takehara, K. Kubo, T. Terasaki, K. Chiba, K. Tomizuka, M. Oshimura:Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans.Hum Mol Genet.22:578-92 (2013)
  8. S. Ohtsuki, C. Ikeda, Y. Uchida, Y. Sakamoto, F. Miller, F. Glacial, X. Decleves, J.M. Scherrmann, P.O. Couraud, Y. Kubo, M. Tachikawa, T. Terasaki:Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.Mol Pharm.10:289-96 (2013)
総説
  1. 伊藤慎悟、大槻純男、寺崎哲也、脳内アミロイドβクリアランスにおける血液脳関門排出輸送分子機構とその破綻。細胞工学 vol.32 No.9 2013年9月号