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活動報告

2012 Publications

2017/03/23
Original Articles
  1. K. Ohmine, K. Kawaguchi, S. Ohtsuki, F. Motoi, S. Egawa, M. Unno, T. Terasaki:Attenuation of phosphorylation by deoxycytidine kinase is key to acquired gemcitabine resistance in a pancreatic cancer cell line: targeted proteomic and metabolomic analyses in PK9 cells.Pharm Res.29:2006-16 (2012)
  2. A. Yoshikawa, M. Nakada, S. Ohtsuki, Y. Hayashi, W. Obuchi, Y. Sato, C. Ikeda, T. Watanabe, Y. Kawahara, T. Hasegawa, H. Sabit, D. Kita, Y. Hayashi, Y. Nakanuma, T. Terasaki, J.I. Hamada:Recurrent anaplastic meningioma treated by sunitinib based on results from quantitative proteomics.Neuropathol Appl Neurobiol.38:105-10 (2012)
  3. S. Ohtsuki, O. Schaefer, H. Kawakami, T. Inoue, S. Liehner, A. Saito, N. Ishiguro, W. Kishimoto, E. Ludwig-Schwellinger, T. Ebner, T. Terasaki:Simultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and Activities.Drug Metab Dispos.40:83-92 (2012)
  4. O. Schaefer, S. Ohtsuki, H. Kawakami, T. Inoue, S. Liehner, A. Saito, A. Sakamoto, N. Ishiguro, T. Matsumaru, T. Terasaki, T. Ebner:Absolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human Hepatocytes.Drug Metab Dispos.40:93-103 (2012)
  5. B. Chakravarthy, C. Gaudet, M. Menard, L. Brown, T. Atkinson, F.M. Laferla, S. Ito, U. Armato, I. Dal Pra, J. Whitfield:Reduction of the immunostainable length of the hippocampal dentate granule cells’ primary cilia in 3xAD-transgenic mice producing human Abeta(1-42) and tau.Biochem Biophys Res Commun.427:218-22 (2012)
  6. S. Ito, M. Menard, T. Atkinson, C. Gaudet, L. Brown, J. Whitfield, B. Chakravarthy:Involvement of insulin-like growth factor 1 receptor signaling in the amyloid-beta peptide oligomers-induced p75 neurotrophin receptor protein expression in mouse hippocampus.J Alzheimers Dis.31:493-506 (2012)
  7. B. Chakravarthy, M. Menard, S. Ito, C. Gaudet, I. Dal Pra, U. Armato, J. Whitfield:Hippocampal membrane-associated p75NTR levels are increased in Alzheimer’s disease.J Alzheimers Dis.30:675-84 (2012)
総説
  1. 大槻純男:抗体に依存しない新しいタンパク質定量技術の個別化治療への応用、実験医学、30:1046-1056 (2012)
  2. 大槻純男:定量的標的プロテオミクスによるファーマコプロテオミクスアプローチ、薬学雑誌、132:479-487 (2012)
  3. 大槻純男:定量的標的プロと恵美楠による生化学の新展開:抗体を用いない汎用的タンパク質定量技術、生化学、84:911-919, 2012