2022

Original Articles

1. 1. A. Mori, T. Masuda, S. Ito, S. Ohtsuki: Human Hepatic Transporter Signature Peptides for Quantitative Targeted Absolute Proteomics: Selection, Digestion Efficiency, and Peptide Stability. Pharm Res. (2022)
   2. T. Masuda, Y. Inamori, A. Furukawa, M. Yamahiro, K. Momosaki, C.H. Chang, D. Kobayashi, H. Ohguchi, Y. Kawano, S. Ito, N. Araki, S.E. Ong, S. Ohtsuki: Water Droplet-in-Oil Digestion Method for Single-Cell Proteomics. Anal Chem. 94:10329-10336 (2022)
   3. Y. Yamasaki, T. Moriwaki, S. Ogata, S. Ito, S. Ohtsuki, G. Minegishi, S. Abe, Y. Ohta, K. Kazuki, K. Kobayashi, Y. Kazuki: Influence of MDR1 gene polymorphism (2677G>T) on expression and function of P-glycoprotein at the blood-brain barrier: utilizing novel P-glycoprotein humanized mice with mutation. Pharmacogenet Genomics. 32:288-292 (2022)
   4. Y. Wang, M. Sakaguchi, H. Sabit, S. Tamai, T. Ichinose, S. Tanaka, M. Kinoshita, Y. Uchida, S. Ohtsuki, M. Nakada: COL1A2 inhibition suppresses glioblastoma cell proliferation and invasion. J Neurosurg. 1-10 (2022)
   5. H. Horiguchi, T. Kadomatsu, S. Yumoto, T. Masuda, K. Miyata, S. Yamamura, M. Sato, J. Morinaga, S. Ohtsuki, H. Baba, T. Moroishi, Y. Oike: Tumor cell-derived ANGPTL2 promotes beta-catenin-driven intestinal tumorigenesis. Oncogene. 41:4028-4041 (2022)
   6. K. Kitamura, A. Okamoto, H. Morio, R. Isogai, R. Ito, Y. Yamaura, S. Izumi, T. Komori, S. Ito, S. Ohtsuki, H. Akita, T. Furihata: Human Immortalized Cell-Based Blood-Brain Barrier Spheroid Models Offer an Evaluation Tool for the Brain Penetration Properties of Macromolecules. Mol Pharm. 19:2754-2764 (2022)
   7. S. Ogata, S. Ito, T. Masuda, S. Ohtsuki: Diurnal Changes in Protein Expression at the Blood-Brain Barrier in Mice. Biol Pharm Bull. 45:751-756 (2022)
   8. H. Nagano, S. Ogata, S. Ito, T. Masuda, S. Ohtsuki: Knockdown of podocalyxin post-transcriptionally induces the expression and activity of ABCB1/MDR1 in human brain microvascular endothelial cells. J Pharm Sci. 111:1812-1819 (2022)
   9. D. Hatakeyama, M. Shoji, S. Ogata, T. Masuda, M. Nakano, T. Komatsu, A. Saitoh, K. Makiyama, H. Tsuneishi, A. Miyatake, M. Takahira, E. Nishikawa, A. Ohkubo, T. Noda, Y. Kawaoka, S. Ohtsuki, T. Kuzuhara: Acetylation of the influenza A virus polymerase subunit PA in the N-terminal domain positively regulates its endonuclease activity. FEBS J. 289:231-245 (2022)
   10. H. Nagano, S. Ito, T. Masuda, S. Ohtsuki: Effect of Insulin Receptor-Knockdown on the Expression Levels of Blood-Brain Barrier Functional Proteins in Human Brain Microvascular Endothelial Cells. Pharm Res. 39:1561-1574 (2022)
   11. Y. Sekimoto, A. Tokai, M. Aritaki, T. Ando, T. Masuda: Objective discrimination of fur type based on electrophoresis optimized for fur‐hair proteins. Electrophoresis (2022)

   Review Article

   1. S. Ogata, T. Masuda, S. Ito, S. Ohtsuki: Targeted proteomics for cancer biomarker verification and validation. Cancer Biomark. 33:427-436 (2022)

   Book Chapter

   1. S. Ito, T. Masuda, S. Ohtsuki: Quantitative and Targeted Proteomics of the Blood-Brain Barrier: Species and Cell Line Differences. in  Drug Delivery to the Brain. Elizabeth C.M. de Lange, Margareta Hammarlund-Udenaes, Robert G. Thorne (Ed.), Springer, pp123-139 (2022)