活動報告

2019

Original Articles

  1. N. Tateshita, N. Miura, H. Tanaka, T. Masuda, S. Ohtsuki, K. Tange, Y. Nakai, H. Yoshioka, H. Akita: Development of a lipoplex-type mRNA carrier composed of an ionizable lipid with a vitamin E scaffold and the KALA peptide for use as an ex vivo dendritic cell-based cancer vaccine. Journal of Controlled Release. 30:36-46 (2019)
  2. S. Ogata, S. Ito, T. Masuda, S. Ohtsuki: Changes of Blood-Brain Barrier and Brain Parenchymal Protein Expression Levels of Mice under Different Insulin-Resistance Conditions Induced by High-Fat Diet. Pharmaceutical research. 36:141 (2019)
  3. M. Nanbu, T. Masuda, S. Ito, K. Kato, T. Kojima, H. Daiko, Y. Ito, K. Honda, S. Ohtsuki: Leucine-rich alpha-2-glycoprotein 1 in serum is a possible biomarker to predict response to preoperative chemoradiotherapy for esophageal cancer. Biol Pharm Bull. Accepted (2019)
  4. E. Takeo, Y. Sugiura, T. Uemura, K. Nishimoto, M. Yasuda, E. Sugiyama, S. Ohtsuki, T. Higashi, T. Nishikawa, M. Suematsu, E. Fukusaki, S. Shimma: Tandem Mass Spectrometry Imaging Reveals Distinct Accumulation Patterns of Steroid Structural Isomers in Human Adrenal Glands.  Anal Chem.  91:8918-8925 (2019)
  5. T. Masuda, T. Hoshiyama, T. Uemura, M. Hirayama-Kurogi, S. Ogata, A. Furukawa, P.O. Couraud, T. Furihata, S. Ito, S. Ohtsuki: Large-Scale Quantitative Comparison of Plasma Transmembrane Proteins between Two Human Blood-Brain Barrier Model Cell Lines, hCMEC/D3 and HBMEC/cibeta.  Mol Pharm.  16:2162-2171 (2019)
  6. T. Kuno, M. Hirayama-Kurogi, S. Ito, S. Ohtsuki: Proteomic analysis of small intestinal epithelial cells in antibiotic-treated mice: Changes in drug transporters and metabolizing enzymes.  Drug Metab Pharmacokinet.  34:159-162 (2019)
  7. S. Ito, G. Honda, Y. Fujino, S. Ogata, M. Hirayama-Kurogi, S. Ohtsuki: Knockdown of Orphan Transporter SLC22A18 Impairs Lipid Metabolism and Increases Invasiveness of HepG2 Cells.  Pharm Res.  36:39 (2019)
  8. Y. Hoshi, Y. Uchida, M. Tachikawa, S. Ohtsuki, P.O. Couraud, T. Suzuki, T. Terasaki: Oxidative stress-induced activation of Abl and Src kinases rapidly induces P-glycoprotein internalization via phosphorylation of caveolin-1 on tyrosine-14, decreasing cortisol efflux at the blood-brain barrier.  J Cereb Blood Flow Metab.  271678X18822801 (2019)
  9. T. Kimura, A. Tsukada, T. Fukutomi, K. Ichida, S. Ohtsuki, H. Sakurai: Urate Transport via Paracellular Route across Epithelial Cells.  Biol Pharm Bull.  42:43-49 (2019)
  10. D. Kobayashi, T. Tokuda, K. Sato, H. Okanishi, M. Nagayama, M. Hirayama-Kurogi, S. Ohtsuki, N. Araki: Identification of a Specific Translational Machinery via TCTP-EF1A2 Interaction Regulating NF1-associated Tumor Growth by Affinity Purification and Data-independent Mass Spectrometry Acquisition (AP-DIA).  Mol Cell Proteomics.  18:245-262 (2019)
  11. S. Nishiumi, T. Kohata, T. Kobayashi, Y. Kodama, S. Ohtsuki, M. Yoshida: Comparison of venous and fingertip plasma using non-targeted proteomics and metabolomics.  Talanta.  192:182-188 (2019)