活動報告

2015 Publications

Original Articles
  1. Y. Uchida, S. Ohtsuki, J. Kamiie, K. Ohmine, R. Iwase, T. Terasaki: Quantitative targeted absolute proteomics for 28 human transporters in plasma membrane of Caco-2 cell monolayer cultured for 2, 3, and 4 weeks. Drug Metab Pharmacokinet. 30:205-8 (2015)
  2. T. Oyama, E. Negishi, H. Onigahara, N. Kusano, Y. Miyoshi, M. Mita, M. Nakazono, S. Ohtsuki, A. Ojida, W. Lindner, K. Hamase: Design and synthesis of a novel pre-column derivatization reagent with a 6-methoxy-4-quinolone moiety for fluorescence and tandem mass spectrometric detection and its application to chiral amino acid analysis. J Pharm Biomed Anal. 116:71-9 (2015)
  3. Y. Uchida, K. Ito, S. Ohtsuki, Y. Kubo, T. Suzuki, T. Terasaki: Major involvement of Na(+) -dependent multivitamin transporter (SLC5A6/SMVT) in uptake of biotin and pantothenic acid by human brain capillary endothelial cells. J Neurochem. 134:97-112 (2015)
  4. K. Ohmine, K. Kawaguchi, S. Ohtsuki, F. Motoi, H. Ohtsuka, J. Kamiie, T. Abe, M. Unno, T. Terasaki: Quantitative Targeted Proteomics of Pancreatic Cancer: Deoxycytidine Kinase Protein Level Correlates to Progression-Free Survival of Patients Receiving Gemcitabine Treatment. Mol Pharm. 12:3282-91 (2015)
  5. Y. Uchida, T. Toyohara, S. Ohtsuki, Y. Moriyama, T. Abe, T. Terasaki: Quantitative Targeted Absolute Proteomics for 28 Transporters in Brush-Border and Basolateral Membrane Fractions of Rat Kidney. J Pharm Sci. 105:1011-6 (2016)
  6. Y. Kaneko, M. Tachikawa, R. Akaogi, K. Fujimoto, M. Ishibashi, Y. Uchida, P.O. Couraud, S. Ohtsuki, K. Hosoya, T. Terasaki: Contribution of pannexin 1 and connexin 43 hemichannels to extracellular calcium-dependent transport dynamics in human blood-brain barrier endothelial cells. J Pharmacol Exp Ther. 353:192-200 (2015)
  7. Y. Kubo, S. Ohtsuki, Y. Uchida, T. Terasaki: Quantitative Determination of Luminal and Abluminal Membrane Distributions of Transporters in Porcine Brain Capillaries by Plasma Membrane Fractionation and Quantitative Targeted Proteomics. J Pharm Sci. 104:3060-8 (2015)
  8. T. Nishina, J. Numata, K. Nishina, K. Yoshida-Tanaka, K. Nitta, W. Piao, R. Iwata, S. Ito, H. Kuwahara, T. Wada, H. Mizusawa, T. Yokota:Chimeric Antisense Oligonucleotide Conjugated to alpha-Tocopherol. Mol Ther Nucleic Acids.4:e220 (2015)