活動報告

2018 Pubilcation

Original Articles

  1. T. Akazawa, Y. Uchida, E. Miyauchi, M. Tachikawa, S. Ohtsuki, T. Terasaki: High Expression of UGT1A1/1A6 in Monkey Small Intestine: Comparison of Protein Expression Levels of Cytochromes P450, UDP-Glucuronosyltransferases, and Transporters in Small Intestine of Cynomolgus Monkey and Human.  Mol Pharm.  15:127-140 (2018)
  2. T. Kuno, M. Hirayama-Kurogi, S. Ito, S. Ohtsuki: Reduction in hepatic secondary bile acids caused by short-term antibiotic-induced dysbiosis decreases mouse serum glucose and triglyceride levels.  Sci Rep.  8:1253 (2018)
  3. K. Sasaki, M. Tachikawa, Y. Uchida, S. Hirano, F. Kadowaki, M. Watanabe, S. Ohtsuki, T. Terasaki: ATP-Binding Cassette Transporter A Subfamily 8 Is a Sinusoidal Efflux Transporter for Cholesterol and Taurocholate in Mouse and Human Liver.  Mol Pharm.  15:343-355 (2018)
  4. E. Miyauchi, T. Furuta, S. Ohtsuki, M. Tachikawa, Y. Uchida, H. Sabit, W. Obuchi, T. Baba, M. Watanabe, T. Terasaki, M. Nakada: Identification of blood biomarkers in glioblastoma by SWATH mass spectrometry and quantitative targeted absolute proteomics.  PLoS One.  13:e0193799 (2018)
  5. S. Nakamura, S.I. Muramatsu, N. Takino, M. Ito, E.F. Jimbo, K. Shimazaki, T. Onaka, S. Ohtsuki, T. Terasaki, T. Yamagata, H. Osaka: Gene therapy for Glut1-deficient mouse using an adeno-associated virus vector with the human intrinsic GLUT1 promoter.  J Gene Med.  20:e3013 (2018)
  6. Y. Yamasaki, K. Kobayashi, F. Okuya, N. Kajitani, K. Kazuki, S. Abe, S. Takehara, S. Ito, S. Ogata, T. Uemura, S. Ohtsuki, G. Minegishi, H. Akita, K. Chiba, M. Oshimura, Y. Kazuki: Characterization of P-glycoprotein Humanized Mice Generated by Chromosome Engineering Technology: Its Utility for Prediction of Drug Distribution to the Brain in Humans.  Drug Metab Dispos.  (2018)
  7. M. Fukuda, T. Yoshizawa, M.F. Karim, S.U. Sobuz, W. Korogi, D. Kobayasi, H. Okanishi, M. Tasaki, K. Ono, T. Sawa, Y. Sato, M. Chirifu, T. Masuda, T. Nakamura, H. Tanoue, K. Nakashima, Y. Kobashigawa, H. Morioka, E. Bober, S. Ohtsuki, Y. Yamagata, Y. Ando, Y. Oike, N. Araki, S. Takeda, H. Mizuta, K. Yamagata: SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix.  Nat Commun.  9:2833 (2018)
  8. T. Yamauchi, T. Masuda, MC. Canver, M. Seiler, Y. Semba, M. Shboul, M. Al-Raqad, M. Maeda, VA. C. Schoonenberg, MA. Cole, C. M. Trevino, Y. Ishikawa, Q. Yao, M. Nakano, F. Arai, SH. Orkin, B. Reversade, S. Buonamici, L. Pinello, K. Akashi, DE. Bauer, T. Maeda: Genome-wide CRISPR-Cas9 screen identifies leukemia-specific dependence on a pre-mRNA metabolic pathway regulated by the DCPS decapping enzyme. Cancer Cell, DOI10.1016/j.ccell.2018.01.012 (2018)
  9. Y. Uchida, T. Sumiya, M. Tachikawa, T. Yamakawa, S. Murata, Y. Yagi, K. Sato, A. Stephan, K. Ito, S. Ohtsuki, P.O. Couraud, T. Suzuki, T. Terasaki: Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis.  Mol Neurobiol.  (2018)
  10. Y. Uchida, T. Sumiya, M. Tachikawa, T. Yamakawa, S. Murata, Y. Yagi, K. Sato, A. Stephan, K. Ito, S. Ohtsuki, P.O. Couraud, T. Suzuki, T. Terasaki: Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis.  Mol Neurobiol. (2018)
  11. H. Maruyama, T. Kimura, H. Liu, S. Ohtsuki, Y. Miyake, M. Isogai, F. Arai, A. Honda: Influenza virus replication raises the temperature of cells.  Virus Res. 257:94-101 (2018)